Guide for Authors

To read or download Instructions to Authors (PDF file), please click here.


Biotechnology and Bioprocess Engineering is an internation-al bimonthly journal published by the Korean Society for Biotechnology and Bioengineering. BBE is devoted to the original and novel findings in the wide area of biotechnology and bioengineering. The editors appreciate contributions relevant to basic and applied research of biotechnology and bioengineering. Contributions are classified as Research Ar-ticles and Reviews. Manuscripts should report new and sig-nificant findings that advance the understanding of applied biology & biochemistry, molecular biology & biomolecular engineering, biocatalysis & biotransformation, combinatorial chemistry, microbiology & metabolic engineering, pharma-ceutics & biomaterials, bioprocess control & system engi-neering, bioseparation, biosensor & bioelectronics, cell cul-ture engineering, environmental biotechnology, food tech-nology, and nanobiotechnology.


Research Articles are research reports of new findings. These papers should not exceed 30 double-spaced pages of text (not including the title and reference pages) and contain a precise description and interpretation of research. Reviews are critical assessments of relevant topics of contemporary interest. These papers should not exceed 60 double-spaced pages of text.

Title Page

The title page of the article should be followed in the order of title, the authors’s name and affiliations and the full correspondence address including telephone, fax, e-mail, etc. The main title should be concise, descriptive and informative to the subject of manuscript and should not exceed more than 150 characters. The running title should be restricted to 50 characters.

Abstract and Keywords

Provide an abstract which states concisely the objectives and the results of the paper in not more than 250 words. It must be a brief and factual account of contents, conclusions, and relevance of the findings with an emphasis on what readers will gain from the manuscript. Do not cite any reference in the abstract. A list of 4-6 keywords for a subject index should be included on this page.

Text Body

(1) The recommended format and the capitalization styles of major headings are as follows: Abstract, Keywords, INTRODUCTION, MATERIALS AND METHODS, RESULTS AND DISCUSSION, CONCLUSION, Acknowledgements, NOMENCLATURE, REFERENCES.

(2) Leave a space between word and parenthesis. Special words of Latin or French origin should be in italic (e.g., in vitro, et al.).

(3) References to published work should be indicated at the appropriate place using brackets (e.g., [2,6-8]), numbered consecutively, and a list of references in numerical order should be provided at the end of the manuscript.

(4) Sources of materials and instruments should be clearly presented together with the names of the appropriate ci-ties and countries.

(5) Units : The SI system should be used for all dimensional quantities. Leave a space between numbers and units except oC and % (e.g., 40 mg/L, 50%, 10 h).

(6) Equations and symbols : Main symbols used in equations and text should be in italic. Superscripts and subscripts should not (e.g., Deff, kLa, Yx/s). Equations must be numbered consecutively using Arabic numbers.

(7) Tables : Type each table on a separate sheet of paper. The table title should have the first letter of the first word capitalized. Details of all necessary additional in-formation can be included in the table footnotes. Pre-ferred font is Arial or Times New Roman with 10 or 12 pt. Table should not contain vertical linings and the cap-tions should be understandable without referring the text.

(8) Figures : Graphs, figures, and other illustrations should be drawn on separate sheets of paper. The uniformity in size of the figures should be maintained carefully. BBE encourages both gray and color illustration as TIFF/EPS files. Use 600 dpi/1200 dpi for illustrations for better clarity. When a figure consists of more than one plot, de-signate each plot as (A), (B), (C), etc. on the upper left-hand side of the plot and refer to it in the text as Fig. 4(A), Fig. 4(B), etc. All figures and lettering must be of a size which remain legible after a 50% reduction of the origi-nal. In the figure caption, only the first letter of the first word in each sentence should be capitalized. Photo-graphs will be accepted if essential to the paper, though an additional charge will be levied. A list of figure cap-tions including explanations of legends should be sup-plied on a separated sheet at the end of the manuscript.

(9) Nomenclature : Symbols used in the text or in equations should be collated and identified with definitions and dimensions. The SI system should be used for all dimensional quantities. Roman symbols are first listed alphabetically, then followed by Greek symbols, superscripts, and subscripts.


All references in this list should be cited at some point in the text. Abbreviate the journal titles as in Chemical Abstracts or Biological Abstracts. References should be presented in the following style :

(1) Journal Articles

Wu, Y. M., V. Kumaran, D. Benten, and S. Gupta (2007) Potential of bioengineering processes for therapeutic repopulation of the liver with cells. Biotechnol. Bioprocess Eng. 12: 1-8.

(2) Books

Sambrook, J., E. Fritsch, and T. Maniatis (1989) Molecular Cloning: A Laboratory Manual. 2nd ed., pp. 23-38. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, USA.

(3) Edited Books

Hamer, G. (1985) Chemical engineering and biotechnology. pp. 356-368. In: I. J. Higgins, D. J. Best, and J. Jones (eds.). Biotechnology: Principles and Applications. Blackwell Scientific, Oxford, UK.

(4) Proceedings/Abstracts

Meyer, H. P., H. J. Kuhn, S.W. Brown, and A. Fiechter (1984) Production of human leucocyte interferon by E. coil. Proceedings of 3rd European Congress on Biotechnology. September 10-14. Munich, Germany.

(5) Dissertations

Han, K. (1992) A Study of Acetic Acid Formation in Escherichia coli Fermentation. Ph.D. Thesis. University of California, Irvine, CA, USA.

(6) Patents

Prudden, J. F. (1977) Method and agent for treating inflammatory disorders of the gastrointestinal tract. US Patent 4,006,224.

(7) Web URL

Korean Society for Biotechnology and Bioengineering, Submission of manuscript.

Note: Manuscripts in which references are not in this format will be returned without review.


Reviews are critical assessments of relevant topics of contemporary interest. Reviews should have a short title and descriptive subtitles. It should present novel ideas and interpretations of established observations. These papers should not exceed 60 double-spaced pages of text. Review articles are commissioned by the Editor and authors desire to submit review articles should consult with the Editor beforehand. Reviews should have a title page, abstract, and references in the same style as Research Articles. The main body should be sectioned at the author's discretion.


Contributions are accepted on the understanding that the authors have obtained the necessary authority for publication. Submission of an article is understood to imply that the article is original and unpublished and is not being considered for publication elsewhere. All papers will be critically read by three reviewers who will be selected for their competence in the subject of matter of the paper.

BBE encourages the electronic submission of the manuscripts via on-line submission system ( The cover letter for submission should include names and addresses of authors, the manuscript title, e-mail address and the phone/fax numbers of the corresponding author, and a brief statement upon the significance of the submitted article. Submitting manuscript can be supplied as an attached file, which is prepared by a popular word processor (Microsoft Word is recommended). Manuscripts should be typed double-spaced on A4 format. In addition, authors should provide a list of three potential reviewers (names/e-mail), none of whom should be affiliated with the authors’ institution(s).


Submission of a manuscript implies: that the work described has not been published before (except in the form of an ab-stract or as part of a published lecture, review, or thesis); that it is not under consideration for publication elsewhere; that its publication has been approved by all co-authors, if any, as well as ? tacitly or explicitly ? by the responsible authorities at the institution where the work was carried out. The author warrants that his/her contribution is original and that he/she has full power to make this grant. The author signs for and accepts responsibility for releasing this material on behalf of any and all co-authors. Transfer of copyright to the Korean Society for Biotechnology and Bioengineering and Springer becomes effective if and when the article is accepted for publication. After submission of the Copyright Transfer Statement signed by the corresponding author, changes of authorship or in the order of the authors listed will not be accepted by the Korean Society for Biotechnology and Bioengineering and Springer. The copyright covers the exclusive right (for U.S. government employees: to the extent transferable) to reproduce and distribute the article, including reprints, translations, photographic reproductions, microform, electronic form (offline, online) or other reproductions of similar nature.

An author may self-archive the English language version of his/her article on his/her own website and his/her institution’s repository; however he/she may not use the publisher’s PDF version which is posted on Further-more, the author may only post his/her version provided acknowledgement is given to the original source of publica-tion and a link must be accompanied by the following text: “The original publication is available at”.

All articles published in this journal are protected by copy-right, which covers the exclusive rights to reproduce and dis-tribute the article (e.g., as offprints), as well as all translation rights. No material published in this journal may be reproduced photographically or stored on microfilm, in elec-tronic data bases, video disks, etc., without first obtaining written permission from the publishers. The use of general descriptive names, trade names, trademarks, etc., in this pub-lication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations.

While the advice and information in this journal is believed to be true and accurate at the date of its going to press, neither the authors, the editors, nor the publishers can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or im-plied, with respect to the material contained herein.

Special regulations for photocopies in the USA: Photocopies may be made for personal or in-house use beyond the limita-tions stipulated under Section 107 or 108 of U.S. Copyright Law, provided a fee is paid. All fees should be paid to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA, Tel.: +1-978-7508400, Fax: +1-978-6468600,, stating the ISSN of the journal, the volume, and the first and last page numbers of each article copied. The copyright owner’s consent does not include copying for general distribution, promotion, new works, or resale. In these cases, specific written permission must first be obtained from the publishers.


BBE adopts the “Uniform Requirements for Manuscripts (URM)” ( produced and updated by the International Committee of Medical Journal Editors (ICMJE)
The Editors expect that new and variant organisms, viruses and vectors described in BBE journals will be made available, under written request and for their own use, to all qualified members of the scientific community. If delays in strain or vector distribution are anticipated or if they are available from sources other than the authors, this should be indicated. The Editors encourage authors to deposit important strains in publicly accessible culture collections and to refer to the collections and strain numbers in the text. In the case of materials that have been distributed by individuals, authors should indicate the laboratory strain designations and name and address of the donor as well as the original culture collection identification number, if any.

Subscription information

ISSN print edition: 1226-8372
ISSN electronic edition: 1976-3816

Volume 15 (6 issues) will appear in 2010

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